Sites need to produce accurate, actionable data, but how can they focus on quality when bogged down with administrative tasks? To keep trials on track, you need superior at-the-source data collection, streamlined workflows, and real-time visibility that lighten site burden while driving protocol compliance. You need the best eSource in clinical trials — which is clearly CRIO.  

A screenshot of the CRIO New eSource “Informed Consent with Re-Consent” page for “Demo Subject 001, Visit 5 (Treatment)” at 7:00 AM, logged in as Amelia Tian.

Header:

Top bar shows “New eSource,” subject name/ID (“Demo Subject 001”), visit (“Visit 5 Treatment”), and user (“Amelia Tian”), with a “View Legend” button on the right.

Left sidebar (vertical nav):

Tabs (white text on dark blue):

Subject Only Consent

Informed Consent with Re-Consent (selected)

SPANISH Version – Informed Consent with Re-consent

Ht/Wt/BMI

Labs

Complete Visit

Progress Notes

Subject Details

Main content area:

Title: “Informed Consent with Re-Consent”

Instructions box (pale yellow) reading “ENTER INSTRUCTIONS FROM PROTOCOL” with an info icon and “Please use Informed Consent Form v3.0 22-Apr-2025.”

Question: “Was the ICF signed and dated by subject at today’s visit?” with radio options “Yes” and “No.”

“Date/Time of signature:” with a date-time picker field.

(Partially visible) next question begins “Was the informed consent executed before any procedures were initiated?”

Launch Signature pop-up (overlay on right):

Title: “Launch Signature”

Radio buttons: “In Person” (selected) and “Remote.”

Instructions: “Please close all other browsers and windows before handing to signee. Upon selecting a method of signing the PIN, the PIN will be sent via the selected method.”

“Current signee: Subject”

“Send pin to:” fields for Phone (2481003200) and Email (demo1@gmail.com).

Footer link: “Not using eConsent this time? Sign consent outside CRIO.”

CRIO is the only eSource platform with central and local site offerings tailored to sponsors, contract research organizations (CROs), and sites. 

For over a decade, clinical research sites, site networks, and academic centers around the globe have used CRIO’s eSource to improve efficiency and guide protocol compliance, delivering higher quality data and fewer protocol deviations.  

CRIO is the leading eSource in clinical trials, delivering 40% higher enrollment, 40% faster startup, and 40% fewer protocol deviations.

eSource Platform

Created by a team of clinical research experts to help sites manage their study protocols from start to finish, our platform helps sites compliantly and efficiently capture source data.  

eSource platform screen

A screenshot of the CRIO web app in the “Data Review” → “Review & Lock” view for the “PLAYGROUND-123 Training” trial. The top nav shows the CRIO logo, a “Master” dropdown, “TRIALS” and “ORGANIZATION” headers, and the user avatar labeled “Amelia Tian.” Below it, the “Data Review” tab is active, with a small multicolor legend and filters for “All” vs. “Need Review Only,” a “Show Read Only” checkbox, and a Subject ID search field. The main panel is expanded for “120 – Amelia Tian – Reviewer Test Site 1” and displays a table with columns: Subject ID, Status, Description, Completed On, Open Queries, and Actions. Three subjects appear: z123 (locked icon) | In Screening | green lock icons for LOG and STATUS, yellow lock icons for Screening and Randomization | dates “31-MAR-2023 12:15 PM EDT” and “03-APR-2024 5:57 PM EDT” | 0 queries | no action YS | In Screening | green square icon for STATUS, yellow square for Screening | date “08-APR-2025 3:21 PM EDT” | 1 query | “Review” link test | Enrolled | green square icon for STATUS | – | 0 queries | “Review” link

EDC Integration

Integrate Central eSource with other third-party EDC systems or use CRIO’s Reviewer EDC for full, native integration. 

Reporting

CRIO offers a comprehensive suite of standard reports, a flexible tool for creating reports within the CRIO platform, a custom report development service, and direct data access that allows clients to use their own business intelligence tools.   

A screenshot of the Looker “Explore” interface with an “Add Filter” modal open in the center.

Background (dimmed):

The Looker logo and “Explore” title sit at the top left.

Beneath, the left sidebar shows the Explore name “Forecast,” a “Find a Field” search box, and a list of available field groups (Custom Fields, Clinical Trial, Forecast, Organization, etc.).

Behind the modal on the right is a dark toolbar with a “Filters” dropdown and, in the top-right corner, a “Time Zone: America – New York” selector and a grey “Run” button.

Add Filter modal:

Title bar reads “Add Filter.”

Directly below is a search field labeled “Search Fields.”

A vertical field tree shows two expandable groups:

Clinical Trial (collapsed)

Forecast (expanded), listing:

Currency Symbol

Is Actual Revenue (Yes / No)

Is for Existing Subject (Yes / No)

Number of Forecasted Subjects

Study Visit Key

Subject Visit Forecast Key (Back End)

Visit Date (collapsible sub-heading)

Visit Holdback

Visit Revenue

Visit Upfront

Below these, in orange text: Total Count (Line Items), Total Holdback, Total Revenue (partially visible)

At the bottom right of the modal is a “Close” link.

Get the eSource you need and watch your studies succeed.

Schedule a Demo