Central eSource Technology for CROs

Central eSource Technology for CROs

Cutting-Edge Source Data Collection

Your clients expect high-quality data and high-performing sites, but it can be challenging to deliver within timelines and budget. There’s an eSource technology that boosts site performance to deliver better, faster data at a lower cost. It’s clearly CRIO.

A screenshot of the CRIO web app’s Data Review “Review & Lock” page for site “PLAYGROUND-123 Training.” At the very top is a dark header bar with the white CRIO logo on the left, a “Master” dropdown, the words “TRIALS” and “ORGANIZATION” in the center, and a user avatar labeled “Amelia Tian” on the right. Below it, a white card shows “PLAYGROUND-123 Training” with a small building icon dropdown at its right. Under that are horizontal tabs—Data Review (highlighted), Queries, Files, Medical Coding, Users—and a second row of sub-tabs with “Review & Lock” selected (others: Progress Notes, Export/Print). A legend strip displays colored status boxes (green, gray, yellow, thumbs-up) next to a “View Legend” link. Beneath, a filter bar reads “View” with an orange “All” button selected and a “Need Review Only” button beside it, plus a “Show Read Only” checkbox and a “Subject ID” search field on the right. The main panel is titled “120 – Amelia Tian – Reviewer Test Site 1” and shows a paginated table (showing 10 entries) with columns: Subject ID, Status, Description, Completed On, Open Queries, Actions. Subject z123 has a red lock icon beside “z123” and status “In Screening” (blue). Under Description it lists two green-locked items—LOG and STATUS—with “––” under Completed On and zero open queries; below those, two yellow-locked items—Screening (completed 31-MAR-2023 12:15 PM EDT) and Randomization (completed 03-APR-2024 5:57 PM EDT)—also with zero queries. Subject YS is “In Screening” and shows a green STATUS square (–– date, 1 open query) and a yellow Screening square (completed 08-APR-2025 3:21 PM EDT, 0 queries), each row ending with a green “REVIEW” action link. Subject test is “Enrolled” (blue) and shows a single green STATUS square (–– date, 0 queries) with a “REVIEW” link. A small “Want to Lock a Subject?” link appears to the right of the legend.

  • 40% fewer protocol deviations

  • 40% higher enrollment

  • 40% faster startup

  • 90% increase in monitoring productivity

Start the conversation

I think of Central eSource as the next evolution in clinical trial efficiency, similar to the shift toward central IRBs and central labs. It ensures high-quality data by standardizing critical data points, yet empowers sites to configure the system to align with their own local practices. Central eSource speeds up study startup considerably. Everyone benefits.

Takoda Roland, Associate Vice President of Customer Success, Sitero

CRIO has been a tremendous partner with Specialty Networks Research, especially in launching our prostate cancer registry across our nationwide network of urology practices. The system is easy to use for the research coordinators and allows our monitoring team to review the source data in real time, ensuring efficiency and consistent quality.

Lorraine O’Donnell, Director, SN Research

ClinCloud was excited to collaborate on a study that integrated eSource data and EDC. With this capability, our site and staff can focus more time on recruiting and retaining patients – what we do best.

Jessica Branning, CEO, ClinCloud

By using CRIO, we deliver significant value to our sponsor clients. CRIO standardizes data collection, eliminates avoidable errors, and allows our monitoring team to review the data continuously, letting us prevent deviations from recurring and improving patient safety.

Takoda Roland, Associate Vice President of Customer Success, Sitero
SEE CRIO IN ACTION

Your eSource Technology for Accuracy & Efficiency

A Central eSource system built by clinical research veterans, CRIO improves site performance, data quality, and monitoring productivity.

Build Compliance at the Source

Central eSource templates automate the protocol, incorporate real-time alerts, and run logic checks to safeguard quality and reduce startup time, while site-level configurability ensures smooth adoption at your sites.

Review Data Remotely in Real Time

Easily access site source data from anywhere as soon as subject visits are completed.  

Improve Site Performance

Central eSource reduces site administrative burden to improve enrollment, accelerate startup, and free your sites to focus on patients.  

A photo looking over a person’s shoulder as they type on a laptop resting on a wooden table. The screen shows the CRIO eSource web app in its “Configure” tab: a grid of study procedures listed down the left and visit phases (“Pre,” “Screening,” “Treatment,” “Follow-up”) across the top, with green checkmarks marking which procedures apply at each phase. In the blurred background, semi-transparent orange and blue hexagon outlines float over a softly lit room.

​CRIO-powered sites out-enroll others by 40% and have 2x the patient diversity

A photo from behind a person typing on a laptop at a wooden desk. On screen is the CRIO Data Review & Lock interface: a dark top bar with the CRIO logo and “PLAYGROUND-123 Training,” the “Data Review” tab highlighted, a small multicolor status legend, and a table listing three subjects (IDs “123,” “YS,” and “test”) with their statuses (“In Screening,” “Enrolled”), description icons for log, status, screening, and randomization, zero open queries, and green “Review” links. Semi-transparent orange and blue hexagons float in the softly lit background.

Maximize Resource Use

Stay on track with simple implementation, intuitive interface, and live, 24/7 support — with people, not bots.  

Get EDC Data Faster With Fewer Queries

Configure your Central eSource template to match your eCRF, integrate with leading EDC vendors, and automate data transmission. 

Win More Studies  

Differentiate yourself from other CROs and reduce downstream risks by embracing innovative technologies with embedded quality design principles. 

Smiling female healthcare professional in blue scrubs holding a tablet and standing in a bright medical facility, with a stethoscope around her neck.

Trial Tested, Site Approved

Worried sites will reject Central eSource? CRIO is already the preferred eSource technology, so it won’t be a problem. Our site enablement services and local source design configuration options have delivered 70% voluntary site adoption on Phase III trials. 

Find out how sites you are already working with use CRIO. 

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Already Have Preferred Vendors?

Our eSource technology seamlessly integrates with leading eClinical technology vendors, making your job even easier.  

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Give sites what they need and watch your study succeed.

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