eSource Reduces Protocol Deviations Compared to Paper Source

With nine locations in Texas, California and Louisiana, and five-time recipient of the Best Clinical Trials Site/Network award from the World Vaccine Congress, Benchmark Research is one of the industry’s leading vaccine network. This white paper provides an in-depth analysis from three participating Benchmark Research. Specifically, results indicate that using CRIO electronic source (eSource) reduces protocol deviations compared to traditional paper source (pSource) in clinical trials. The reduction rate was nearly 40%, demonstrating that the adoption of CRIO improves data quality and enhances patient safety. This improvement is attributed to CRIO’s system features, including real-time edit checks and automated error-detection processes.

Beyond reducing protocol deviations

CRIO’s impact extends beyond just minimizing protocol deviations. It also safeguards patient privacy, standardizes processes across data holders, delivers large data volumes, and enhances cost efficiency. Decreased protocol deviations result in fewer downstream effects, such as reduced data cleaning times and lower costs for corrective action plans. This efficiency could allow sponsors and study stakeholders to redirect resources into other areas of clinical research.

eSource vs paper

Further, CRIO eSource improves the quality assurance process compared to traditional pSource methods. With pSource, quality control personnel often need to scan, email, and annotate paper charts. This created delays between data capture and quality control. Conversely, with CRIO, the Quality Assurance team can review data shortly after its collection or even in real-time during an ongoing study visit. CRIO’s electronic system allows multiple stakeholders to simultaneously access data from various locations, thus streamlining global workflows.

What’s next?

CRIO offers a more efficient and reliable alternative to traditional pSource methods in clinical trials. By improving data quality, patient safety, recruitment, and stipend management for patients, CRIO enhances the overall experience for all involved parties. Download the complete white paper to see the details of the analysis.

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