CRIO is transforming clinical trials by reimagining workflows from the site’s perspective. We challenge the status quo and push boundaries, harnessing our commitment to excellence, hands-on experience, and site-empowering expertise to build quality at the point of capture and unlock significant downstream benefits for all research stakeholders.
The eSource system that’s built for sites and better for trials is clearly CRIO.

Our Mission
Our mission is to design and deliver a modern, intuitive, and integrated software platform that reimagines clinical trials for quality, speed, and patient centricity.
A History of Innovation, a Future of Possibilities
Since 2015, CRIO has been leading the charge in eSource technology, optimizing research operations with breakthrough solutions.
2015
CRIO
Founded in 2015 by current Co-CEO Raymond Nomizu and Phuc Truong
2016
eSource
The first-ever widely used, site-based eSource solution
2018
eSource — Finance Integration
Automatically tying revenue and cost to completed source procedures
eSource — eDOA Integration
First electronic delegation of authority (eDOA) log tied to eSource permissions
2021
Publisher
A centralized application for creating, versioning, and pushing study templates to sites around the world
2022
Reviewer — Dual Database
First dual-database solution in which sites have their own protected health information (PHI)-enriched solution and sponsors have a global solution with anonymized study data
Direct Data Access
Giving site networks direct access to their segregated datasets
2023
Research-Care Integration
Innovative partnership with Pluto Health to connect care and research
2024
Partners Program
Providing an ecosystem of qualified site services providers and integrated technology providers to CRIO clients
2025
Central eSource
Sponsors and CROs can harness the benefits of site technology to power their clinical trials
What’s Next for CRIO?
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Our Community Partners: Improving Research Together
CRIO’s commitment to improving clinical trials goes beyond eSource technology. We partner with organizations to help create more inclusive, accessible, and helpful research for all.
Meet Our Technology Partners
CRIO also works with leading research technology providers to further enable sites and optimize clinical trials.