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Standardizing clinical trial source creation

Customize, version and publish source templates to sites

Build and publish study templates rapidly

Use CRIO’s extensive and customizable library of best-in-class, site-oriented eSource templates to build study protocols in hours, not days. Version and publish to sites as needed.

Build quality at point of capture

Use instructions, edit checks and branching logic to guide the site through the protocol and flag unexpected values. Build quality directly into the data collection process. Use real-time alerts to preempt deviations, and then convert any disregarded alerts into auto-queries!

Build templates collaboratively with sites

While the templates published are edit locked for the site, individual sites can add their own custom visits, procedures or questions, thus incorporating their own workflows! For instance, some sites can build a prescreening visit if that's their SOP.


Join the industry’s leader in electronic source data capture for clinical trial sites. CRIO eSource is a user-friendly, web-based tool to capture site source data in real-time.

Discover eSource

CRIO Publisher allows sponsors, networks and other users running the same study at multiple sites to build, version and push the templates to the sites on the trial.

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CRIO Reviewer allows sponsors and CROs to review eSource data as it's saved, and to query, lock, medical code and extract the data. It's a remote monitoring and EDC tool rolled into one.

Discover Reviewer EDC

CRIO’s eConsent automates the completion and execution of the Informed Consent, and is built right into CRIO’s eSource workflow.

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With CRIO’s eRegulatory, research sites can streamline regulatory workflows with paperless binders and an electronic delegation log.

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CRIO’s innovative partnership with Pluto Health Health delivers electronic medical records, alongside clinical care insights, straight to the investigator, within minutes! PIs can review health data and insights, and annotate the data before entry into source and the EDC.

Discover Medical Record API

CRIO's reporting module lets users filter, sort, search, download, schedule and export data. Users can also have their own Business Intelligence tool query their CRIO data directly.

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CRIO’s site-based CTMS lets clinical research sites run their "back office operations", including patient recruiting, scheduling, financial management and more.

Discover Site CTMS

Sites can issue and load patient stipend cards with preset or manual amounts. Our reports keep track of how much you’ve paid each subject, enabling easy 1099 reporting.

Discover Patient Stipends