The Platform of Choice for High-Performing Research Sites
You need to produce reliable, protocol-driven data, but how can you focus on quality when you’re bogged down with administrative details and manual tasks? There’s a clinical research technology that optimizes your performance with at-the-source data collection, streamlined operations, 24/7 customer service, and real-time visibility. It’s clearly CRIO.

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33% time savings
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40% higher enrollment
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40% fewer protocol deviations
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70% lower audit risk
Your Clinical Research Technology for Better Performance
An eSource platform built by a former site owner, CRIO makes it all easier.
Build Quality at the Source
Highly configurable, easy-to-build eSource templates automate the protocol, incorporate real-time alerts, and run built-in checks to stop mistakes before they happen.
Optimize Operations
- Single-point data capture reduces duplicative work and administrative burden, improving enrollment, accelerating startup, and allowing you to focus on patients
- Integrated finances keep receivables up to date and streamline invoices and payments
- eRegulatory solution eliminates paper binders, reduces deviations, and enables remote collaboration
CRIO-powered sites out-enroll others by 40% and have 2x the patient diversity
Quickly Recruit & Schedule
- Integrated patient recruitment solutions send text blasts, enable interactive prescreening questionnaires, and pull web leads directly into the system and more
- Automated window tracking schedules visits and pre-programs appointment reminders to keep patient visits on track
Intuitive Clinical Research Technology
Built for Sites by a Site
Prior to cofounding CRIO, our co-CEO owned and operated a clinical research site — giving us unique insights into the real-world site experience.
Trial Tested, Site Approved
2,000+ sites use the CRIO platform on 6,000+ protocols for over 800 sponsors in 28 different countries.
Go Further, Faster, With CRIO
Our clinical research technology seamlessly integrates with leading site service providers, patient recruitment and retention vendors, and other eClinical technology providers, further optimizing your operations.